In silico investigation of symptom development model based on coat protein interactions of two cucumber mosaic virus strains

Cucumber mosaic virus (CMV) causes serious diseases in agricultural crops worldwide, predominantly vegetable and ornamental plants. A critical interaction has been reported between the plant Ferredoxin I (Fd I) protein with coat (CP) of M strain CMV (M-CMV) but not by CP Q (Q-CMV). To ascertain most likely symptom development model based on interacting Fd protein, further silico investigation was performed CPs strains Q-CMV M-CMV. The biological assembly virions is composed hexameric pentameric units. results showed that there were significantly different interactions forms I. Pentameric structural M-CMV interact strongly compared to structures CP, while no significant differences affinities for CPs. it can be deduced probably block activation protein. Therefore, could hypothesized trapping complex lead inhibition activity photosynthetic electron transport chain leading severe seen infected plants It seems any factor inhibits prevent this development. • Different M− CP. Trapping Factors inhibit CP-induced